Abstract: In 2000, Darmon described a remarkable program to study the Generalized Fermat equation Ax^r + By^q = Cz^p using modularity of abelian varieties of GL2-type over totally real fields. However, this program relies on various hard conjectures, making it impractical, and until recently it has been successfully applied only in cases where the abelian varieties were elliptic curves. In this talk, we will discuss how to combine the classical modular method using elliptic curves with Frey hyperelliptic curves due to Kraus and ideas from the Darmon program to study the Fermat-type equations of the form x^r + y^r = C z^p.